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Life Extension Natural Estrogen With Pomegranate 60 Tabs
MMH ID: 26754; Brand: Life Extension; Model No: 00712

Life Extension Natural Estrogen With Pomegranate 60 TabsMouse-over to zoom; click to expand
Price:  $38.00

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60 caplets

In an attempt to provide aging women with the multiple health effects of the bodies’ estrogen without side effects, scientists have discovered plant extracts with estrogenic activity (phytoestrogens).

Natural Estrogen with Pomegranate Extract is one answer to the concerns of maintaining healthy hormone function. A review of the published literature reveals some interesting findings about how plant-derived estrogens can provide safe and effective support for such menopausal symptoms as hot flashes.

Derived from organically-grown fruit, the pomegranate extract in this formula has the same ratio of polyphenols found in the whole fruit and all the benefits one would get from the juice without the sugar, calories, and additives. Punicalagins, the main polyphenol responsible for pomegranate’s health properties, has been shown to be a powerful antioxidant. In fact, the health effects from the juice and the seeds work synergistically providing an array of health benefits.

Scientists have identified specific extracts from cruciferous vegetables (broccoli, cauliflower, Brussels sprouts, etc.) that modulate hormones in a way to help maintain healthy cell division. For instance, animal studies have shown that the cruciferous vegetable extract indole-3-carbinol (I3C) modulates estrogen hormones by favorably changing the ratio of protective 2-hydroxyestrone versus the damaging 16-hydroxyestrone. Found abundantly in broccoli, indole-3-carbinol also induces phase I and II detoxifying enzymes that can help neutralize estrogen metabolites and xenobiotic estrogen-like environmental chemicals. Human studies support the beneficial role of I3C in positively altering estrogen metabolism. Di-indolyl-methane (DIM), a phytonutrient found in cruciferous vegetables, has been shown in animal studies to help maintain normal levels of a potentially damaging estrogen called 4-hydroxyestrone. The glucosinolates are major constituents of cruciferous vegetables that have been shown to promote normal apoptosis and induce the expression of the beneficial p53 gene via an estrogen-independent action.

HMRlignan™ is a powerful antioxidant and free radical scavenger. A naturally occurring plant lignan, HMRlignan’s major component, 7-hydroxymatairesinol, is a precursor to enterolactone, a human lignan found throughout the body that acts as to protect the body from excess estrogen and its unwanted effects. Enterolactone may also limit excess cell growth in specific tissues and has also been linked to beneficial effects in menopausal women. Thus, the addition of the phyto-nutrient HMRlignan may prove beneficial to human health.

Also included in the formula is a soy extract—Soyselect® —that significantly enhances the bioavailability of isoflavones because of its double standardized of isoflavone glycosides genistin and daidzin.

This formulation of Natural Estrogen with Pomegranate Extract contains broccoli extract and HMRlignan™ in addition to phytoestrogens and other plant extracts, all of which have proven to provide optimal female hormonal support.

Supplement Facts

Serving Size 2 caplets

Servings Per Container 30

Amount Per Serving

SoySelect® soybean (Glycine max) 70:1 Extract

400 mg

[standardized to 13% isoflavones (52 mg), 18% Group-B Saponins (72 mg)]


Broccoli (Brassica oleracea l.) Super Concentrate Extract

300 mg

(plant) [standardized to 4% glucosinolates (12 mg)]


PomElla® Pomegranate (Punica granatum) Extract (fruit)

200 mg

[standardized to 30% Punicalagins (60 mg)]


Black cohosh extract (Cimicifuga racemosa) (root and

40 mg

rhizome) [standardized to 2.5% triterpene glycosides (1 mg)]


HMRlignan™ Norway spruce (Picea abies) lignan extract

30 mg

(knot wood) [standardized to 90% Hydroxymatairesinol potassium acetate complex (27 mg)]


Dong quai extract (Angelica sinensis) (root)

25 mg

[std. to 1% ligustilide (.25 mg)]


Licorice extract (Glycyrrhiza glabra) (root)

25 mg

Vitex extract (Vitex agnus-castus ) (fruit)

20 mg

[std. to 5% vitexicarpin (1 mg)]


Other ingredients: dicalcium phosphate, microcrystalline cellulose, stearic acid, croscarmellose sodium, silicon dioxide, magnesium stearate, pharmaceutical glaze.

Contains soybeans. Contains corn. This product contains NO milk, egg, fish, peanuts, crustacean shellfish, tree nuts, wheat, yeast, gluten, or rice. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.

SoySelect® is a registered trademark of Indena S.p.A.
HMRlignan™ is a trademark used under sublicense from Linnea S.A.
PomElla® is a registered trademark of Geni Herbs.

Dosage and Use

Take two caplets in the morning with or without food, or as recommended by your healthcare practitioner.

NATURAL ESTROGEN should be taken cyclically: three weeks on and one week off, beginning on the 5th day of the menstrual cycle for premenopausal women, and every day for postmenopausal women.

Those taking any estrogenic product should include as part of their diet cruciferous vegetables such as broccoli, Brussel sprouts, cabbage and/or cauliflower.

Women should also use a natural progesterone cream when taking this product.


Do not take in case of pregnancy, lactation, or estrogendependent tumors.


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