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Epidermal Growth Factor BT
MMH ID: 45146; Brand: DIY Skincare; Model No: 38S

Epidermal Growth Factor BTMouse-over to zoom; click to expand

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Price:  $17.86

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Where Is This Active Ingredient Found? Epidermal Growth Factor BT is the active ingredient in ReVive skin care line.

Product Description & Benefits:
In 1986, Stanley Cohen received the Nobel Prize for his work elucidating the role of the Epidermal Growth Factor (EGF) in the regulation of cell growth and development. EGF is a growth factor that plays an important role in the regulation of cell growth, cell proliferation and differentiation. As with all growth factors, it is a small protein. EGF acts by binding to specific receptors on the cell surface, starting a cascade of very organized molecular events, including increased intracellular calcium concentration, energy production and protein synthesis. Application of EGF to the skin will accelerate healing and, when applied to aging skin, it will increase the rate of skin renewal, which decreases with age. View the Certificate of Analysis for our current batch of EGF.

This is one the specialty proteins (see also

KGF and

SOD) made by Skin Actives Scientific using biotechnology. Biotechnology is a short name for an array of sophisticated methods that allow scientists to make large amounts of a single protein, nearly pure and fully active, at a fraction of the cost of extracting it from the original source material. Please note that our growth factors are sold for use in cosmetics only. Please ask us about wholesale pricing as well as custom protein development.

What is a growth factor? Growth factors, a.k.a. citokines, are naturally occuring proteins capable of stimulating cellular proliferation and cellular differentiation. Growth factors bind to specific receptors on the cell surfaces and are important for the regulation a variety of cellular processes. Among the practical uses of EGF are its use in accelerating healing of skin and cornea. EGF was the first growth factor to be discovered and studied, but many more factors have been found since then. These growth factors differ in size and structure, affecting different receptors and types of cells as a consequence, and causing various effects on the target cells.

This skin care active ingredient is made by a licensed, high-quality laboratory of skin care ingredients. Make Me Heal has partnered with leading laboratories and manufacturers of skin care ingredients to come up with the largest assortment of high-quality active ingredients that are effective for your skin. These ingredients are backed by scientific research and testing.

What's Do It Yourself (DIY) Skin Care?


DIY Skin Care is an emerging trend in the beauty world where consumers are taking control of their skin care regimen and are making their own home-based recipes of skincare products by combining scientifically proven active ingredients inside creams. DIY presents an opportunity to create affordable beauty products at your home and to try different ingredients to arrive at recipes that are the most optimal for your skin needs. You can use DIY to simply copy well-known, expensive creams and make your own cheaper home version, or to combine your favorite cream with an ingredient that you've found to be beneficial.

Directions For Use:
Each kit is enough for 4 fl oz of cream or lotion at approximately 0.00005% concentration (50 mcg in 120 mL cream). Use in your favorite cream or add to our Canvas Base Cream or a Sea Kelp Bioferment base. Mix thoroughly, but gently. Vigorous mixing will decrease the activity level of the EGF. EGF is kept highly concentrated to preserve its activity, therefor you will hardly see the EGF drop at the bottom of the small tube. Store the EGF in the refrigerator until you are ready to use it. When ready to use, add the contents of the second tube (saline solution) to the tube containing EGF and close. Mix by inverting and straightening the tube several times. The EGF is now ready for addition to your cream, lotion, or serum. Do not be tempted to use it more concentrated than recommended. A growth factor is similar to a hormone: very little (it is measured in micrograms, one millionth of a gram) will go a very long way.

Franklin J D; Lynch J B (1979) PLASTIC AND RECONSTRUCTIVE SURGERY Effects of topical applications of epidermal growth factor on wound healing. Experimental study on rabbit ears, 64(6), 766-70.

Mustoe, Thomas A.; Pierce, Glenn F.; Morishima, Chihiro; Deuel, Thomas F. (1991) Growth factor-induced acceleration of tissue repair through direct and inductive activities in a rabbit dermal ulcer model. Journal of Clinical Investigation , 87(2), 694-703.

Ricotti, G.; Tappa, M. M.; Tucci, M. G.; Pugnaloni, A.; Lucarini, G.; Biagini, G.; Bertani, A.; Toschi, E.; Castaldini, C. (1993) Tissue expansion improvement: the role of epidermal growth factor. Clin. Dermatol., Journal of Materials Science: Materials in Medicine (1993), 4(4), 345-52.

Grahn, Jennifer C.; Isseroff, R. Rivkah. (2004) Human melanocytes do not express EGF receptors. Journal of Investigative Dermatology, 123(1), 244-246.

Mimura, Yoshihiro; Ihn, Hironobu; Jinnin, Masatoshi; Asano, Yoshihide; Yamane, Kenichi; Tamaki, Kunihiko (2004) Epidermal growth factor induces fibronectin expression in human dermal fibroblasts via protein kinase C d signaling pathway. Journal of Investigative Dermatology, 122(6), 1390-1398.


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  • Our Products Are Researched, Tried-And-Tested By Patients, Recommended By Doctors: The healing products available at Makemeheal.com have been tried and tested and shown to be beneficial to consumers and patients during their preparation and recovery. We also find some products through our extensive research and recommendations from doctors. The skin care, beauty, and anti-aging products sold on Make Me Heal are among the leading doctor-recommended products that have been found to have the highest benefits in wrinkle reduction, maintenance of healthy skin, and beauty.

Make Me Heal Surgery Healing Supplements & Vitamins Kit (Pre & Post-Op Formulas)

This Pre & Post Op Multinutrient Kit (with Bromelain; no Vitamin E) has been designed specifically to help patients accelerate healing and obtain better cosmetic results following plastic surgery (as well as general surgeries) by providing all the vital healing supplements, vitamins, minerals, antioxidants, and amino acids that have been shown to be vital for preparing the body for surgery and for helping one have a faster recovery. Taken in tablet/pill form starting anywhere from 1-2 weeks pre-op or several days before the surgery up until 30 days post-op, the Multinutrient Kit helps build and maximize your body’s tissue reserves of nutrients that are important for the healing process, helps speed up recovery by strengthening the body’s natural healing process, helping reduce swelling and bruising, supporting wound healing, promoting repair and growth of tissues damaged by surgery, and by protecting the body from infection by enhancing the immune system defenses. Appropriate for both women and men of all ages.