Where Is This Active Ingredient Found? Niacinamide is the active ingredient in the Hylexin skin care line.
Product Description & Benefits:
Niacinamide (nicotinamide for chemists) is part of coenzymes essential for metabolism. Because we cannot make it, we must acquire Niacinamide from outside sources, making it by definition, a vitamin. Even if we obtain enough Niacinamide through food and multivitamin supplements, application topically is beneficial. As skin ages, the body no longer supplies enough nutrients to the skin, partly because the density of blood vessels reaching the dermis decreases. Also, application of Niacinamide topically has been shown to benefit skin color, decrease melanin synthesis (important for hyperpigmentation), and decrease inflammation and itching (pruritus). The biochemical effects of Niacinamide include increased concentration of NADPH, the donor of reducing power in cell biosynthesis, an effect that translated in incraesed synthesis of collagen, involucrin, filaggrin, and keratin. Topical application of Niacinamide also decreased UV-induced skin cancers and prevented immunosuppression by UV irradiation. The effect of Niacinamide on inflammation is through inhibition of histamine release by mast cells, neutrophil chemotaxis, and release of inflammatory mediators. Niacinamide will also help with skin infections in diabetics. Please note that application of niacinamide is contra-indicated for people affected by Parkinson disease.
This skin care active ingredient is made by a licensed, high-quality laboratory of skin care ingredients. Make Me Heal has partnered with leading laboratories and manufacturers of skin care ingredients to come up with the largest assortment of high-quality active ingredients that are effective for your skin. These ingredients are backed by scientific research and testing.
What's Do It Yourself (DIY) Skin Care?
DIY Skin Care is an emerging trend in the beauty world where consumers are taking control of their skin care regimen and are making their own home-based recipes of skincare products by combining scientifically proven active ingredients inside creams. DIY presents an opportunity to create affordable beauty products at your home and to try different ingredients to arrive at recipes that are the most optimal for your skin needs. You can use DIY to simply copy well-known, expensive creams and make your own cheaper home version, or to combine your favorite cream with an ingredient that you've found to be beneficial.
Directions For Use:
Each tube is enough for 32 fl oz of cream or lotion at approximately 0.5% concentration (5 g in 960 mL cream). Use in your favorite cream or add to our Canvas Base Cream or a Sea Kelp Bioferment base.
Hakozaki T; Minwalla L; Zhuang J; Chhoa M; Matsubara A; Miyamoto K; Greatens A; Hillebrand G G; Bissett D L; Boissy RE (2002) The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. The British journal of dermatology 147(1): 20-31.
Soma, Yoshinao; Kashima, Masato; Imaizumi, Akiko; Takahama, Hideto; Kawakami, Tamihiro; Mizoguchi, Masako. (2005) Moisturizing effects of topical nicotinamide on atopic dry skin. International Journal of Dermatology,44(3): 197-202.
Gensler, Helen L. (1997) Prevention of photoimmunosuppression and photocarcinogenesis by topical nicotinamide. Nutrition and Cancer (1997), 29(2), 157-162.