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The Auto Refill Program gives you great price discounts and the convenience of having this item shipped automatically to you on a regular basis based on how often you want to receive it. By using this program, you will receive the price discount displayed on this description page for every auto refilled shipment sent after your initial order. We will ship the item automatically to the address you specify and charge the credit card on record. You save time and money with the Auto Refill Program. You can cancel the program anytime. To activate the auto-ship program, simply select the desired refill frequency from the drop-down menu on this page. The discount is not offered to non-auto refill customers.

MMH ID: 45208; Brand: DIY Skincare; Model No: 75S

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Price:  $15.98

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Where Is This Active Ingredient Found? Niacinamide is the active ingredient in the Hylexin skin care line.

Product Description & Benefits:
Niacinamide (nicotinamide for chemists) is part of coenzymes essential for metabolism. Because we cannot make it, we must acquire Niacinamide from outside sources, making it by definition, a vitamin. Even if we obtain enough Niacinamide through food and multivitamin supplements, application topically is beneficial. As skin ages, the body no longer supplies enough nutrients to the skin, partly because the density of blood vessels reaching the dermis decreases. Also, application of Niacinamide topically has been shown to benefit skin color, decrease melanin synthesis (important for hyperpigmentation), and decrease inflammation and itching (pruritus). The biochemical effects of Niacinamide include increased concentration of NADPH, the donor of reducing power in cell biosynthesis, an effect that translated in incraesed synthesis of collagen, involucrin, filaggrin, and keratin. Topical application of Niacinamide also decreased UV-induced skin cancers and prevented immunosuppression by UV irradiation. The effect of Niacinamide on inflammation is through inhibition of histamine release by mast cells, neutrophil chemotaxis, and release of inflammatory mediators. Niacinamide will also help with skin infections in diabetics. Please note that application of niacinamide is contra-indicated for people affected by Parkinson disease.

This skin care active ingredient is made by a licensed, high-quality laboratory of skin care ingredients. Make Me Heal has partnered with leading laboratories and manufacturers of skin care ingredients to come up with the largest assortment of high-quality active ingredients that are effective for your skin. These ingredients are backed by scientific research and testing.

What's Do It Yourself (DIY) Skin Care?


DIY Skin Care is an emerging trend in the beauty world where consumers are taking control of their skin care regimen and are making their own home-based recipes of skincare products by combining scientifically proven active ingredients inside creams. DIY presents an opportunity to create affordable beauty products at your home and to try different ingredients to arrive at recipes that are the most optimal for your skin needs. You can use DIY to simply copy well-known, expensive creams and make your own cheaper home version, or to combine your favorite cream with an ingredient that you've found to be beneficial.

Directions For Use:
Each tube is enough for 32 fl oz of cream or lotion at approximately 0.5% concentration (5 g in 960 mL cream). Use in your favorite cream or add to our Canvas Base Cream or a Sea Kelp Bioferment base.

Hakozaki T; Minwalla L; Zhuang J; Chhoa M; Matsubara A; Miyamoto K; Greatens A; Hillebrand G G; Bissett D L; Boissy RE (2002) The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. The British journal of dermatology 147(1): 20-31.

Soma, Yoshinao; Kashima, Masato; Imaizumi, Akiko; Takahama, Hideto; Kawakami, Tamihiro; Mizoguchi, Masako. (2005) Moisturizing effects of topical nicotinamide on atopic dry skin. International Journal of Dermatology,44(3): 197-202.

Gensler, Helen L. (1997) Prevention of photoimmunosuppression and photocarcinogenesis by topical nicotinamide. Nutrition and Cancer (1997), 29(2), 157-162.

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Benefits of Getting This Product At Makemeheal.com

  • Our Products Are Researched, Tried-And-Tested By Patients, Recommended By Doctors: The healing products available at Makemeheal.com have been tried and tested and shown to be beneficial to consumers and patients during their preparation and recovery. We also find some products through our extensive research and recommendations from doctors. The skin care, beauty, and anti-aging products sold on Make Me Heal are among the leading doctor-recommended products that have been found to have the highest benefits in wrinkle reduction, maintenance of healthy skin, and beauty.

MakeMeHeal Surgery Healing Supplements & Vitamins Kit (Pre & Post-Op Formulas)

This Pre & Post Op Multinutrient Kit (no Vitamin E) has been designed specifically to help patients accelerate healing and obtain better cosmetic results following plastic surgery (as well as general surgeries) by providing all the vital healing supplements, vitamins, minerals, antioxidants, and amino acids that have been shown to be vital for preparing the body for surgery and for helping one have a faster recovery. Taken in tablet/pill form starting anywhere from 1-2 weeks pre-op or several days before the surgery up until 30 days post-op, the Multinutrient Kit helps build and maximize your body’s tissue reserves of nutrients that are important for the healing process, helps speed up recovery by strengthening the body’s natural healing process, helping reduce swelling and bruising, supporting wound healing, promoting repair and growth of tissues damaged by surgery, and by protecting the body from infection by enhancing the immune system defenses. Appropriate for both women and men of all ages.